Barron Associates envisions significant near- and far-term uses for the proposed use of the system safety case for certification. The Food and Drug Administration, for example, requires the delivery of an assurance argument --- a synonym for the safety case --- with any new direct-injection drug pumps. The increase in the amound of software present in unmanned systems make traditional certification approaches both challenging and expensive; the results of the empirical study will inform future decision making regarding how certification should be pursued. Beyond air vehicles, other classes of unmanned systems, including ground and underwater vehicles will also benefit from the technology. Finally, the nuclear industry depends upon software for the control of its power plants and propulsion systems. Techniques like the system safety case, which directly argue software safety, may bring benefit as compared to prescriptive approaches, which only claim software quality. The proposed new, modular collision-avoidance system also has applications beyond those envisioned for NASA. In addition to its applications for civil air transport, the modularity of the system make it suitable for Department of Defense use in sense-and-avoid applications: ADS-B could be replaced by an active surveillance capability, such as one that relied on an on-board radar.