Non-NASA: Night Vision, Mass spectrometry, Photoionization, Electron microscopy, Surface physics, UV and VUV imaging, Fusion research, Synchrotron Radiation, Nuclear physics, Field ion microscopy, Low temperature physics, Neutron Detectors, Neutron Radiography and Tomography, Scanning Near field Microscopy, Accelerators , Plasma Physics, Cluster research, Fluorescent detection and Trace analysis. NASA: Substrate independence, large area detectors, single event detection in a single MCP (no chevron required), greatly improved resolution and direct deposition of opaque photocathodes have the potential for enormous impact on NASA missions. These innovations will contribute to improved resolution and optics simplification. By significantly improving functionality & capability of MCPs, a single plate configuration capable of low noise, high resolution counting and imaging that could surpass existing detector performance benchmarks becomes possible. A significant reduction of size, mass, power and cost of detection enabling smaller, more affordable spacecraft while benefitting science measurement capabilities allowing NASA programs can to meet multiple mission needs making the best use of limited resources.