Potential NASA Commercial Applications: The Individualized Stress Detection System will meet the specific requirements of long duration exploration missions and provide feedback to astronauts, Op Psy personnel and flight surgeons about stress levels and hyperarousal as well as aid in the selection of countermeasures. It will be designed to be unobtrusive and to require minimal training and crew effort to utilize. The resulting product will be primarily relevant to NASA's Behavioral Health and Performance (BHP) research gap BMED 2: "What are the most effective methods to predict, detect, and assess decrements in behavioral health (which may negatively affect performance) before, during, and after spaceflight missions?" The resulting product will also be relevant to gaps BMED1, BMED6, and BMED7. When validated, the Individualized Stress Detection System will be deployed on ISS to support crew behavioral health during training, mission, and return to Earth.