The proposed polymer microfluidics and optical technologies can be readily adapted to NASA's miniature "Micro Laboratories" scientific instrumentations for in-situ exploration of the solar system. In particular, it is directly applicable to analyze PAH and other neutral organic molecules on Mars and Titan surfaces. The proposed technology has other broad NASA applications including on-chip biosensors, electrochemical sensors, wet-chemistry systems, as well as high pressure micropumps for fluid positioning, mixing, metering, storage, and filtering systems. In addition, the novel microfluidics technology is naturally suited to such applications as clinical diagnostics, spacecraft and biosphere environmental monitoring, and toxicology studies. The microfluidics technology described in this proposal is directly applicable for terrestrial analysis for PAH molecules in health and environmental studies. Compared to existing micellar electrokinetic chromatography and reverse-phase HPLC, the microCEC technology described in this proposal offers a natural alternative providing inexpensive, rapid, nondestructive, in-situ techniques for the measurement of PAH contamination in sediments. Additional commercial devices based on such microfluidics technology envisioned include components for DNA, protein and drug separation and analysis, chemical analysis systems, drug delivery systems, and embedded health monitoring systems.