Electrical checkout and testing is a critical part of the overall spacecraft integration and test flow. Verifying proper harness and connector signal interfaces is key to ensuring component health and overall system functionality. Break-Out Boxes (BOB) are used to give test personnel access to electrical signals for probing, voltage injection, isolation checks, safe-to-mate checks, and voltage/current measurements. Currently this involves manually attaching multimeters and oscilloscopes to banana jacks on the BOB, taking measurements and comparing to expected results. Tiger Innovations proposes designing an automated break-out box to make electrical integration activities more efficient, repeatable, and safe by introducing software controlled test sequences and reducing human errors. Additionally, significant schedule and cost reductions are realized by improving the speed and reliability of integration operations. Our software controlled BOB would allow isolation and safe-to-mate checks to be accomplished in a fraction of the time required for a human operator. Voltage and current measurements would be analyzed in the software for pass/fail criteria and reported to the user for inclusion in the test log. Automating test sequences through the use of an automated BOB has the potential to significantly streamline spacecraft, payload and launch site electrical integration and test activities.