Illuminex Corporation proposes a NASA Phase I SBIR project to develop high performance, lightweight, low-profile heat pipes with enhanced thermal transfer properties enabled by utilizing copper nanowire arrays as the wick material in the heat pipe. Thermal management is a critical issue for advanced electronic and optical systems as current cooling techniques are being rapidly outpaced by the heat load of new technologies. Superior thermal control technologies are needed both for NASA's science spacecraft components and commercial products such as computers and medical lasers. The incorporation of nano-structured materials in heat pipe manufacturing will allow the development of thermal management devices with increased heat dissipation efficiency and a reduced size and weight profile as compared to currently utilized cooling approaches. Illuminex will develop processes to engineer the nanowire wick directly onto the heat pipe package, and using this approach, it s envisioned that heat pipe systems can be manufactured directly into the housings of devices requiring advanced thermal management. This nanotechnology enabled miniaturization can be further size reduced to near the MEMS level for cooling micro-electronics and sensors. Phase II will lead to full commercialization and manufacturing of high performance, low profile, and lightweight heat pipes.