Combining smart sensor with wireless technology is a compelling addition to structure a large-scale smart sensor networks for real-time data acquisition, distributed detection and estimations. This requires a distributed data acquisition and control system containing edge-sensing devices to interact with different types of sensors, which poses significant challenges to the system architect. Mobitrum is proposing an innovative solution to fill the gap between sensing devices and data acquisition system by offering an end-to-end architecture and methods to interface with edge devices and to present data that they generated. The effort includes: (1) Object-oriented approach to interfaces with standard-based smart sensors and smart transducer interface modules (STIM), (2) Advanced intelligent data acquisition and control, (3) Sensor health assessment, (4) Data management and intelligent sensor fusion across local and mobile computational platforms. The significance of the innovation is that the new system can significantly lower the cost and increase the capabilities to improve remote testing and safety assurance.