Distributed Reconfigurable Intelligent software agent technologies are key and revolutionary technologies that are needed to fulfill spacecraft autonomy and robustness operations capabilities and functions. The Distributed Reconfigurable Intelligent spacecraft autonomy and robustness system integrates real time control and health monitoring with planning and scheduling to achieve the long-term mission objectives. This project develops the Distributed Reconfigurable Intelligent software agents consisting of automation in multi levels, knowledge base, inference mechanism, and communication. The proposed Distributed Reconfigurable Intelligent software agents for operations assistant takes advantage of innovative techniques of individual decision and control methodologies and emphasizes the synergism among all subsystems to assure the overall system performance. At the end of the project, a demonstration system will be established to evaluate the proposed software system.