Techshot has a more than 25-year-history of developing and integrating spaceflight hardware, and it serves as an official Implementation Partner to NASA and CASIS. The company's success with microgravity facilities such as the Avian Development Facility, the Advanced Space Experiment Processor and the Bone Densitometer position it as a leader in offering these unique services. When coupled with the innovative capabilities of other research devices aboard the ISS, the Snap Freezer will give NASA an even greater ability to serve the investigator community it supports. Furthermore, with the ability of commercial launch vehicles to get more experiment samples into orbit, the economics of transporting and processing materials in microgravity should become far more compelling. Eventually, given sufficient economical commercial launch vehicle transporting capacity, when coupled with Techshot's cadre of space processing equipment, the Snap Freezer could become an important tool for processing larger quantities of high-value materials for NASA customers aboard ISS. Our product is expected to be of particular interest to the pharmaceutical and biotechnology industries, academic researchers and terrestrial national laboratories, and Techshot is committed to investing in its commercialization. Beginning with this Phase I award, the company will build a technology demonstrator with internal funds. While typical laboratories snap freeze tissues by plunging specimens into liquid nitrogen or an isopentane bath chilled by liquid nitrogen, this may not be compatible with all experimental protocols or facility safety standards, which will provide commercial opportunities. Much like the safety concerns on the ISS, significant burn hazards exist from liquid nitrogen spills and isopentane is an extremely flammable liquid. When these conditions exist in terrestrial labs, researchers use cold blocks to freeze samples. But even actively-cooled plates in cryostats do not typically reach temperatures sufficient for effective snap freezing. This may not freeze sensitive or thick tissues at a fast enough rate to preserve the most sensitive DNA, RNA, proteins and crystal structures.