The rHEALTH X can be utilized onboard the ISS to perform science. These applications include non-invasive measurements of cells and small animals, temperature monitoring of experiments, 4-parameter flow cytometry applications, multiplexed gene expression analysis using nanostrips, biomarker measurements of cell changes, flexible assay capability for space research community, and use of rHEALTH X in Microgravity Sciences Glovebox or Disposable Glove Bag to solve sample transfer issue. The rHEALTH X will aid crew members on the ISS and for travel to Mars. Capabilities allow for rapid monitoring of immune alterations from radiation, bone loss from microgravity environments, kidney health based on metabolites, cardiac rhythm disturbances, sleep alterations, and other critical and emergent conditions that may affect the health and safety our crew members. In addition, the technology can be broadly utilized to track body health and performance in cabin and EVA. Other crew health application include real-time monitoring of astronaut health status, heart rate monitoring to detect arrhythmias, temperature to assess infection or fever, respiratory rate to determine breathing capability, SpO2 to measure respiratory function, study of bone health via 25-OH vitamin D, assessment of immune function via TNFα, study of space radiation effects, systematic monitoring of astronaut health status, acute determination of trauma and blood loss. The rHEALTH X will have a transformative effect on the delivery of diagnostic information. This includes real-time health monitoring, providing rapid diagnosis, measurement of leukocytes to diagnose infection and inflammation, portable EKG to allow immediate measurement of heart rate and rhythms, temperature to assess infection and fever, respiratory rate to measure breath capability, SpO2 to measure oxygenation and breathing changes, acute determination of trauma and blood loss, comprehensive portable health monitor with tripartite capabilities, healthcare diagnosis at home and in the field, consumer health management. The rHEALTH X will enable the democratization of biomedical diagnostics.