There is an extraordinary need for a universal biomedical analyzer that has broadly flexible capabilities for cell studies, small animal experiments, and crew member health. The goal of our rHEALTH X device is to create a single palm-sized device with tripartite capabilities: non-invasive measurements, cell cytometry analysis, and multiplexed nanostrip tests. Currently, there is no single device that is able to provide comprehensive non-invasive measurements, let alone combine it with the rHEALTH's significant wet laboratory analytical capabilities. We have developed the existing rHEALTH technology in collaboration with NASA and here, in this Phase II proposal, we intend to further push the envelope and develop a fully integrated solution. The non-invasive module will include measurements of heart rate, SpO2, body temperature, respiratory rate, and EKG. The module will be housed in the back of the rHEALTH X and will be fully detachable for wireless/wearable applications. The main unit will provide wet laboratory capabilities for cells and nanostrips. At the end of Phase II, we will deliver a rHEALTH X with vitals patch to NASA and bring it up to TRL 7, so that it can be flight-certified and flown on the International Space Station (ISS) in a timely manner.