This project was completed with a total of 16 volunteers, 8 control subjects (Group 1), and 8 treatment subjects (Group 2). Data analysis was completed, and a manuscript has been submitted for consideration of publication in a peer-reviewed scientific journal. Results from this work indicate that wearing the abdomen-high compression garments during an 80-degree head-up tilt test (Groups 1 and 2) prevented the orthostatic intolerance that is normally present after BR. Thigh-high garments (Group 2) provided some protection after BR, and wearing these garments did not impair recovery as measured by a tilt test three days after bed rest. (Ed. note: updated report provided by PI August 2013.)More »
Findings from this study have the potential to impact treatment of patients who are hypotensive and/or suffer from episodes of orthostatic intolerance. Commercially-available knee-high and thigh-high compression garments, while easy to don and convenient to wear, have limited effectiveness as previously tested in our laboratory. The commercially-available breast-high garment, while an effective protection against orthostatic intolerance, can be difficult to don, uncomfortable, and/or inconvenient to remove to urinate or defecate. In contrast, the three-piece garment developed for this project provides the same amount of coverage as the commercially-available breast-high garment but provides greater levels of compression than the commercially-available breast-high garment, is an effective countermeasure to orthostatic intolerance, is easy to don and doff, and can be more easily adjusted for comfort. The improvements to the wear and comfort realized in the development of the three-piece garments should enhance compliance with long-term wearing of compression garments, reduce hypotensive episodes, and improve the lifestyle of patients with orthostatic intolerance. A cardiologist who treats these types of patients has complimented the investigator team on the design of the test garment, and the manufacturer of the modified garment has applied for a US patent.More »
|Organizations Performing Work||Role||Type||Location|
|Johnson Space Center (JSC)||Lead Organization||NASA Center||Houston, TX|
A final report document may be available for this project. If you would like to request it, please contact us.