Numerical cavitation modeling capability is critical in the design of liquid rocket engine turbopumps, feed lines, injector manifolds and engine test facilities. Cavitation in turbopumps leads to reduced performance, mechanical vibrations, and component erosion. The Computational Fluid Dynamics (CFD) solver Loci-STREAMdeveloped by Streamline Numericsis one of the primary production tools currently used at NASA to simulate turbopumps. With a long term goal of enabling accurate computational modeling of cavitating turbopumps subjected to an array of potential operating conditions, this project is aimed at enhancing the cavitation modeling capability in Loci-STREAM to enable time-accurate simulations involving complex engineering geometries present in turbopumps of relevance to NASA involving cryogenic fluids (LOX, LH2, LCH4, RP-1, RP-2). This will contribute to enhanced performance, reliability and reduced developmental costs of liquid rocket pumps. The project will involve a tightly coupled experimental/computational effort. The experimental simulations will be conducted at the University of Florida in a dedicated experimental facility capable of investigating various cavitation modes covering the entire range of non-cryogenic to cryogenic fluids; the proposed studies will be supported by extensive instrumentation. The cavitation models in Loci-STREAM will be substantively validated via dedicated experimental data directed by the computational and model requirements.