NASA's "Ground Systems Development and Operations Program" is moving towards transforming parts of the Kennedy Space Center from a historically government-only launch complex to a spaceport bustling with activities involving government and commercial vehicles alike. The success of this transformation drive largely depends on achieving the ability to process multiple types of vehicles, within a rather short time and in an economic way. QSI proposes developing a COTS (Commercial off-the-Shelf) Software to facilitate 'Plug and Play Real-time Diagnosis for Ground Processing System Integration' to support achieving the objective of the program. QSI will add capabilities to their TEAMS (Testability Engineering and Maintenance System) toolset such that it will enable NASA to perform diagnostic analysis for various vehicular and ground systems without the requirement to build the analytic models and software tools from ground-up. Here, NASA is only required to build the diagnostic models (required for system integration, testing, assembly, maintenance/troubleshooting and pre-launch checkout) of the systems. Upon building, those can be used in a plug-and-play fashion through the analytic/diagnostic environment of TEAMS in conjunction with monitored data and test results from the vehicular and ground systems for obtaining diagnostic, prognostic, time to alarm, time to maintenance, etc. decisions.