NASA's interest in CubeSat missions is driven by the need to do high-quality science with a limited budget. NASA is at the threshold of producing fully instrumented CubeSats for less than $0.8M each. To be effective, these must use technologies that are small, consume little power, and avoid risks associated with high voltages and electronic complexity. Therefore, the impact of the detectors that are enabled by our DEM is likely to be very significant for NASA. The new detectors enable low-cost implementations of new ideas that revolutionize Space Applications, like the new WINCS suite for ionosphere-thermosphere missions that provides the function of 4 spectrometers with performance levels exceeding previous instruments, all in a package less than 3x3x3 inches cubed with total power less than 1.6 Watts. Similarly, renewed interest in planetary and inter-stellar science requires measurements of neutral atoms in Space (e.g., LENA in the IMAGE spacecraft) that will require DEM to take advantage of new detectors. Such applications will require careful characterization of this new generation of detectors using the experimental method implemented in DEM - to ensure proper experimental design in such missions, discriminating photons from neutrals and ions. As with the potential for NASA applications, the intrinsic value of our Detector Evaluation Module is extended by its broad vacuum pressure range to entirely new spectrometers, including mass spectrometers, that are just beginning to offer solutions in many commercial areas: medical diagnosis, industrial process monitoring, volcanology, environmental monitoring of pollutants in air and water, and military value for detection of chemical, biological agents and explosives. DEM will provide the detector data required for such new applications of the Graphene and other chemical sensors in a new generation of mass spectrometers that do not require high vacuum as traditional mass spectrometers do.