In Subtopic X11.01, NASA has identified the need to develop advanced radiation-shielding materials and systems to protect humans from the hazards of space radiation during NASA missions. The radiation components of interest include protons, alpha particles and heavy ions from galactic cosmic rays, protons and other ions from solar particle events, high energy electrons and neutrons, and high-energy electromagnetic radiation. International Scientific Technologies, Inc., in conjunction with the College of William and Mary, proposes to raise the technology readiness level of selected polymeric radiation-shielding materials through participation in the Materials on the International Space Station Experiment program, named MISSE-X. The Phase I SBIR program demonstrated the feasibility of developing a flight-qualified Technology Demonstration Experiment to be carried on board the ISS as part of a MISSE-X payload to facility Technology Infusion. Phase II Technical Objectives will include specification and fabrication of polymeric materials to shield astronauts and sensitive electronic equipment, acquisition and test of detectors/dosimeters suitable for measurement of total ionizing dose, design, construction, test and optimization of an experimental package compatible with the guidelines and specifications of the MISSE-X program, and field testing and integration in conjunction with NASA personnel and NASA contractors. The anticipated result of the Phase II program is the delivery of an experiment package for MISSE-X.