As a result of technological breakthroughs, research and applications in the Terahertz (THz) radiation system are experiencing explosive growth. The non-ionizing and penetrative nature of THz radiation makes it promising for detection in the medical imaging applications. The THz image can be identified as markers of malignant tissues. Because the requirements for THz instruments are very ambitious, there is a need for new nano-antenna configurations, and for refining existing configurations and technologies for top performance. In this study, we will investigate various THz nano-antennas to improve the performance of the nano-antenna with innovative designs. The objective of this study is to highlight current and emerging research in the THz nano-antenna fields, as well as applications of this technology.