Monitoring Radiation-Induced DNA Degradation
Project Description
The MEMS (Micro Electro-Mechanical Systems) Radiation project is developing a miniaturized microfluidic (lab-on-a-chip) device that is designed to monitor DNA damage, in real-time, resulting from radiation exposure in space. The instrument under development will (a) use the polymerase chain reaction (PCR) to amplify DNA, (b) thermally image the micro?device to monitor thermal gradients for proper thermal exposure, and (c) use fluorescent imaging to monitor radiation?induced changes in DNA composition. The ultimate goal is to help understand the details of radiation exposure in space and potentially serve as a radiation rapid warning device for astronauts.
More »Anticipated Benefits
There is currently no flight-ready DNA melting analysis hardware available in a low-G environment. Hardware will be used to determine, in real time, the level of DNA damage caused by radiation in the spaceflight environment. Potential users of the matured technology include ISS space biology researchers and medical professionals on Earth.
More »Primary U.S. Work Locations and Key Partners
| Organizations Performing Work | Role | Type | Location |
|---|---|---|---|
Kennedy Space Center
(KSC)
|
Lead Organization | NASA Center | Kennedy Space Center, Florida |
Primary U.S. Work Locations
-
Florida
