Development of a Wide-Spectrum Organic Analysis Instrument, Year 1

Modifying a two-step laser mass spectrometer (ultra-L2MS) to enable in situ micrometer-scale analysis of diverse organic molecules with sub-femtomole sensitivity. With previous IRD support we designed and constructed a vacuum ultraviolet (VUV) laser source, which enables efficient, soft, single-photon ionization of organic molecules. We incorporated this VUV ion source with our instrument and have successfully measured hundreds of organic molecules on test samples. The modified instrument is unique and enables the measurement of organic molecules with an unprecedented combination of sensitivity and spatial resolution. In FY'13 we expanded our analysis of samples to include astromaterials and biological materials relevant to international space station (ISS) and human space flight (HSF). We are also in the process of integrating our existing UV laser photoionization source with the new VUV source to enable both to be operated simultaneously. By combining VUV photons with UV/Visible photons we can explore the use of novel two-photon (118.2 nm + 1064/532/355/266 nm) resonant and non-resonant ionization schemes. By timing the photons from both sources to arrive simultaneously in the ionization region of the ultra-L2MS instrument we can further the expanding of the range of detectable molecular species. Additionally by allowing a controlled delay between the arrival of photons from the two sources (time-delayed two-photon ionization) it may also be possible to provide structural information for certain molecular species that could not be provided by conventional mass spectrometry techniques. More »