Any complex system must diagnose faults and use procedures to recover capabilities. This is true of aircraft, ships, petrochemical plants, oil refineries, nuclear power plants, etc. Many of these industries are still using manual procedures and simple fault diagnosis with no prognosis or data mining. TRACLabs has worked with industry leaders such as Honeywell and Foxboro to research applying NASA-developed procedure technology to a variety of industries. Vanderbilt has worked closely with Boeing Phantom works to develop model-based reasoning and data mining capabilities for aircraft maintenance. We will expand these ties and search for additional markets for these capabilities. Given the tens of thousands of aircraft, ships, power plants and processing plants worldwide the market for these technologies is enormous. Long duration space missions, such as Lunar outposts, will require significantly improved system health management systems due to their distance from ground controllers and the expectation that they will be uncrewed for certain periods of time. Integration of data- and model-based diagnosis and prognosis systems with procedure-based systems will enable new system health management capabilities for NASA. This will result in more efficient operation of space vehicles such as Orion, Ares, Altair, Lunar habitats and Lunar rovers. Several existing NASA programs can make immediate use of this technology including: CxPASS, ConFRM, A4O, LSS and MCT.