Potential NASA Commercial Applications: Distant planetary rovers communicate with scientists only intermittently because of limited visibility and availability of Earth-based antennas. As the number of spacecraft needing attention grows and spacecraft longevity increases, this bandwidth constraint will only get worse. It is therefore critical to maximize the information content in each transmission. Autonomy can improve productivity in intervals between communication opportunities and increase science data returned. In particular, science autonomy makes decisions affecting the scientific measurements that will be collected or transmitted. There is a need for smart software that intelligently targets, acquires, analyzes, and compresses imaging spectroscopy data. We will to apply the state of art in science autonomy, including the recent work at Carnegie Mellon in areas of automatic spectrometer targeting and spectra collection, science-guided path planning, and orbital terrain classification, to the creation of Intelligent Spectrometry for Robotic Explorers (ISRE). ISRE will enable real-time analysis of spectroscopic data to guide spectrometer targeting. This involves selecting rover navigation goals and directing a spectrometer foreoptic to measure the intended target rock or soil. In this way, the most informative science targets will be automatically sampled, the quality of the science data return will improve, abd the required scientist effort and necessary communication bandwidth will be reduced.