We propose to design, build, and test a two-stage waste processing reactor for space applications. Our proposed technology converts waste from space missions into hydrogen, water, carbon monoxide, carbon dioxide that can be used for energy production and/or life support. This innovative reactor technology employs a pyrolysis reactor as the first step, followed by a chemical looping gasification reactor as the second step. The two-stage process is more suitable than the traditional one-step gasification process, because solid residues associated with the waste, such as ash and tar, are contained in the pyrolysis unit. The utilization of metal oxides that can be readily obtained at the site of exploration as an oxidizer in the gasification (second) step instead of traditional oxidizers such as oxygen or steam further saves the valuable resources that can be used for life support systems or other space applications. If successful, our innovation can fully utilize natural (metal oxides) and discarded (wastes from space missions) materials that may exist during space exploration, thus saving the valuable oxygen or water that can be used for life support systems or other space applications.