Maneuverable pico-satellites have many potential NASA commercial applications. For example, swarms or formations of pico-satellites could provide global real-time space weather monitoring in a way that is presently not possible from a single satellite. Autonomous rendezvous and docking technology could perform on-orbit inspection of a nearby vehicle. The relatively low-cost and rapid access to space of pico-satellites enables lower cost on-orbit testing of new components, allowing quicker and more reliable progression to higher Technology Readiness Levels. Pico-satellite maneuverability and control is a key, often required aspect of mission performance. Non-NASA federal agencies and commercial ventures will benefit from maneuverable pico-satellites. Rapid response communications, imaging, and situational awareness solutions are needed by the Department of Defense, National Reconnaissance Office, and Department of Homeland Security. DARPA's F6 program is an example of a fractionated spacecraft formation application that can be addressed with pico-satellites. Low cost and rapid access to space will also improve the profitable realization of new commercial space applications. Commercial applications such as on-orbit spacecraft servicing and direct to user remote sensing are viable. The mission return will be substantially improved with reliable low-cost pico-satellite maneuverability.