{"projectId":5004,"project":{"projectId":5004,"title":"On-Demand Urine Analyzer, Phase II","startDate":"2004-12-02","startYear":2004,"startMonth":12,"endDate":"2006-12-02","endYear":2006,"endMonth":12,"programId":73,"program":{"ableToSelect":false,"acronym":"SBIR/STTR","isActive":true,"description":"<p>The NASA SBIR and STTR programs fund the research, development, and demonstration of innovative technologies that fulfill NASA needs as described in the annual Solicitations and have significant potential for successful commercialization. If you are a small business concern (SBC) with 500 or fewer employees or a non-profit RI such as a university or a research laboratory with ties to an SBC, then NASA encourages you to learn more about the SBIR and STTR programs as a potential source of seed funding for the development of your innovations.</p><p><strong>The SBIR and STTR programs have 3 phases</strong>:</p><ul><li><strong>Phase I</strong> is the opportunity to establish the scientific, technical, and commercial feasibility of the proposed innovation in fulfillment of NASA needs.</li><li><strong>Phase II</strong> is focused on the development, demonstration and delivery of the proposed innovation.</li></ul><p>The SBIR and STTR Phase I contracts last for 6 months with a maximum funding of $125,000, and Phase II contracts last for 24 months with a maximum funding of $750,000 - $1.5 million.</p><ul><li><strong>Phase III</strong> is the commercialization of innovative technologies, products, and services resulting from either a Phase I or Phase II contract. Phase III contracts are funded from sources other than the SBIR and STTR programs and may be awarded without further competition.</li></ul><p><strong>Opportunity for Continued Technology Development Post-Phase II</strong>:</p><p>The NASA SBIR/STTR Program currently has in place two initiatives for supporting its small business partners past the basic Phase I and Phase II elements of the program that emphasize opportunities for commercialization. Specifically, the NASA SBIR/STTR Program has the Phase II Enhancement (Phase II-E) and Phase II eXpanded (Phase II-X) contract options.&nbsp;</p><p><strong>Please review the links below to obtain more information on the SBIR/STTR programs.</strong></p><ul><li><strong><a target=\"_blank\" href=\"http://sbir.gsfc.nasa.gov/sites/default/files/ParticipationGuide.pdf\">Participation Guide</a></strong></li></ul><p>Provides an overview of the SBIR and STTR programs as implemented by NASA</p><ul><li><strong><a href=\"http://sbir.gsfc.nasa.gov/solicitations\">Program Solicitations</a></strong></li></ul><p>Provides access to the annual SBIR/STTR Solicitations containing detailed information on the program eligibility requirements, proposal instructions and research topics and subtopics</p><ul><li><strong><a href=\"http://sbir.gsfc.nasa.gov/prg_sched_anncmnt\">Schedule and Awards</a></strong></li></ul><p>Schedule and links for the SBIR/STTR solicitations and selection announcements</p><ul><li><strong><a href=\"http://sbir.gsfc.nasa.gov/content/additional-sources-assistance\">Sources of Assistance</a></strong></li></ul><p>Federal and non-Federal sources of assistance for small business</p><ul><li><strong><a href=\"http://sbir.gsfc.nasa.gov/abstract_archives\">Awarded Abstracts</a></strong></li></ul><p>Search our complete archive of awarded project abstracts to learn about what NASA has funded</p><ul><li><strong><a href=\"http://sbir.gsfc.nasa.gov/content/frequently-asked-questions\">Frequently Asked Questions</a></strong></li></ul><p>&nbsp;Still have questions? Visit the program FAQs</p>","parentProgram":{"ableToSelect":false,"isActive":true,"description":"Catalyst is a portfolio of early stage programs that specialize in different innovation constituencies and mechanisms to push the state of the art in aerospace technology development","programId":92327,"responsibleMd":{"canUserEdit":false,"locationEdit":false,"organizationRolePretty":"","organizationTypePretty":""},"title":"Catalyst","acronymOrTitle":"Catalyst"},"parentProgramId":92327,"programId":73,"responsibleMd":{"organizationId":4875,"organizationName":"Space Technology Mission Directorate","acronym":"STMD","organizationType":"NASA_Mission_Directorate","canUserEdit":false,"locationEdit":false,"organizationRolePretty":"","organizationTypePretty":"NASA Mission Directorate"},"responsibleMdOffice":4875,"stockImageFileId":36648,"title":"Small Business Innovation Research/Small Business Tech Transfer","acronymOrTitle":"SBIR/STTR"},"description":"The overall goal of this program (through Phase III) is to develop an analyzer that can be integrated into International Space Station (ISS) toilets to measure key chemicals in urine.  The analyzer will employ a novel metal-doped sol-gel material to both separate these key chemicals from urine and provide surface-enhanced Raman spectra to identify and quantify these chemicals.  The Phase I program successfully demonstrated feasibility by chemically extracting 3-methyl histidine, a muscle-loss indicator, and raloxifene a bone-loss inhibitor from simulated urine.  In flowing experiments, both chemicals were measured at 10 nanogram/mL, below the required detection limit of 1000 ng/mL for 3-methyl histidine, and near the required detection limit of 1 ng/mL for raloxifene.  The Phase II program will develop the method of analysis using some 50 bio-indicators, drugs and metabolites, and potential interfering urine components.  The program will also design and build an automated extraction, measurement and analysis system suitable for integration into Hamilton Sundstrand's proposed ISS toilets.  Hamilton Sundstrand has agreed to an on-site demonstration that includes initial measurements using the proposed analyzer and their equipment to initiate a Phase III collaboration. 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